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步宏

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189

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发表于 2017-6-30 15:23:45 | 显示全部楼层 |阅读模式
步宏

主任医师

步宏,四川大学华西医院病理科教授、博士生导师、病理研究室主任,四川大学副校长。
现任职务:病理研究室主任,四川大学副校长。国务院学位委员会学科评议组成员。
现任职称:教授,博士生导师。
学术任职:现任中华医学会病理学分会主任委员[1] 、中国抗癌协会肿瘤病理专业委员会主任委员、卫生部全国病理质控中心专家委员会副主任委员、卫生部全国肿瘤规范化诊疗专家委员会委员。《中华病理学杂志》、《临床与实验病理学杂志》、《中国肺癌杂志》、《诊断病理学杂志》等期刊常务编委和编委。教育部教学评估专家,教育部学科建设委员会委员,教育部医学人文教指委副主任委员。
亚专业:从事乳腺病理及分子病理学诊断和研究。专业业务工作主要是引领乳腺疾病小组开展对乳腺疾病的病理诊断、分子病理诊断及研究工作。并承担医学生和研究生的授课工作。
工作经历
1982年毕业于宁夏医学院。
1982~1993年历任原华西医科大学病理教研室/病理科助教、讲师。
1992~2005年任病理教研室/病理科副主任,病理实验室主任。
1993年在原华西医科大学获医学博士学位,同年晋升副教授。
1994年赴香港大学研修。
2000年晋升教授。
2001年遴选为博士生导师。
科研成果
科研成果:作为负责人和主研人员近年获国家973计划项目、国家自然科学基金重大项目、国家自然科学基金面上项目、教育部博士点基金等10余项资助,以第一作者和通讯作者已发表SCI收录论文100余篇。曾获国家教学成果二等奖和四川省科技进步一等奖及二等奖多项。获全国百篇优博论文指导教师奖。
主要论文
Q, Li Y, Wang Y, Li L, Jiang X, Tang J, Yang H, Zhang J, Bao J, Bu H. The effect of heparinized decellularized scaffolds on angiogenic capability. J Biomed Mater Res A. 2016 Dec;104(12):3021-3030. doi: 10.1002/jbm.a.35843. PubMed PMID:27459086.[1]&
Deng S, Jin T, Zhang L, Bu H, Zhang P. Mechanism of tacrolimus-induced chronic renal fibrosis following transplantation is regulated by ox-LDL and its receptor, LOX-1. Mol Med Rep. 2016 Nov;14(5):4124-4134. doi: 10.3892/mmr.2016.5735. PubMed
PMID: 27633115.
Li Y, Wang Y, Wu Q, Li L, Shi Y, Bu H, Bao J. Comparison of methods for isolating primary hepatocytes from mini pigs. Xenotransplantation. 2016 Sep;23(5):414-20. doi: 10.1111/xen.12259. PubMed PMID: 27596934.
Kong L, Zhou Y, Bu H, Lv T, Shi Y, Yang J. Deletion of interleukin-6 in monocytes/macrophages suppresses the initiation of hepatocellular carcinoma in mice. J Exp Clin Cancer Res. 2016 Sep 2;35(1):131. doi:10.1186/s13046-016-0412-1. PubMed PMID: 27589954; PubMed Central PMCID: PMC5009700.
Zhong X, Xie G, Zhang Z, Wang Z, Wang Y, Wang Y, Qiu Y, Li L, Bu H, Li J, Zheng H. MiR-4653-3p and its target gene FRS2 are prognostic biomarkers for hormone receptor positive breast cancer patients receiving tamoxifen as adjuvant endocrine therapy. Oncotarget. 2016Aug 13. doi: 10.18632/oncotarget.11278. PubMed PMID: 27533459.
Zhu M, Bu H, Peng YL. Letter to the Editor: Vascular tumor versus vascular malformation of the internal auditory canal. J Neurosurg. 2016 Sep;125(3):785. doi: 10.3171/2016.3.JNS16657. PubMed PMID: 27419829.
Bao J, Wu Q, Wang Y, Li Y, Li L, Chen F, Wu X, Xie M, Bu H. Enhanced hepatic differentiation of rat bone marrow-derived mesenchymal stem cells in spheroid aggregate culture on a decellularized liver scaffold. Int J Mol Med. 2016 Aug;38(2):457-65.
Lu F, Chen Y, Zhao C, Wang H, He D, Xu L, Wang J, He X, Deng Y, Lu EE, Liu X, Verma R, Bu H, Drissi R, Fouladi M, Stemmer-Rachamimov AO, Burns D, Xin M, Rubin JB, Bahassi el M, Canoll P, Holland EC, Lu QR. Olig2-Dependent Reciprocal Shift in PDGF and EGF Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma. Cancer Cell. 2016 May 9;29(5):669-83. doi:
10.1016/j.ccell.2016.03.027. PubMed PMID: 27165742; PubMed Central PMCID: PMC4946168.
Wang Y, Bao J, Wu X, Wu Q, Li Y, Zhou Y, Li L, Bu H. Genipin crosslinking
reduced the immunogenicity of xenogeneic decellularized porcine whole-liver matrices through regulation of immune cell proliferation and polarization. Sci Rep. 2016 Apr 21;6:24779. doi: 10.1038/srep24779. PubMed PMID: 27098308; PubMed Central PMCID: PMC4838870.
Yang L, Wang Y, Shi Y, Bu H, Ye F. Deletion of SIP1 promotes liver regeneration and lipid accumulation. Pathol Res Pract. 2016 May;212(5):421-5. doi: 10.1016/j.prp.2016.02.015. PubMed PMID: 26936023.
Wang E, Zhu M, Bu H, Chen J, Ding Y, Zhou X, Liang Z, Zhang X, Sun B; Thoracic Disease Study Group of Chinese Society of Pathology.; Molecular Pathology Study Group of National Health and Family Planning Commission Pathology Quality Control Center.; Molecular Pathology Study Group of Chinese Pathologist Association.; Molecular Pathology Study Group of Chinese Anti Cancer Association of Tumor Pathology.. [Consensus of Chinese experts on detection of related drive genes in target therapy of non-small cell lung cancer]. Zhonghua Bing Li Xue Za Zhi. 2016 Feb;45(2):73-7. doi: 10.3760/cma.j.issn.0529-5807.2016.02.001. Chinese. PubMed PMID: 26879425.
Zhou Y, Zhang L, Ji H, Lu X, Xia J, Li L, Chen F, Bu H, Shi Y. MiR-17~92 ablation impairs liver regeneration in an estrogen-dependent manner. J Cell Mol Med. 2016 May;20(5):939-48. doi: 10.1111/jcmm.12782. PubMed PMID: 26781774ubMed Central PMCID: PMC4831359.
Chinese Society of Pathology, Chinese Pathologist Association, Committee of Oncopathology of Chinese Anticancer Association, Pathology Quality Control Center of China, National Steering Committee of Molecular Pathology.; Chinese Society of Pathology Chinese Pathologist Association Committee of Oncopathology of Chinese Anticancer Association Pathology Quality Control Center of China National
Steering Committee of Molecular Pathology.. [Guideline of construction of molecular pathology laboratory]. Zhonghua Bing Li Xue Za Zhi. 2015 Jun;44(6):369-71. Chinese. PubMed PMID: 26704828.
Qiu Y, Pu T, Guo P, Wei B, Zhang Z, Zhang H, Zhong X, Zheng H, Chen L, Bu H, Ye F. ALDH(+)/CD44(+) cells in breast cancer are associated with worse prognosis and poor clinical outcome. Exp Mol Pathol. 2016 Feb;100(1):145-50. doi: 10.1016/j.yexmp.2015.11.032. PubMed PMID: 26687806.
Pu T, Guo P, Qiu Y, Chen S, Yang L, Sun L, Ye F, Bu H. Quantitative real-time polymerase chain reaction is an alternative method for the detection of HER-2 amplification in formalin-fixed paraffin-embedded breast cancer samples. Int J Clin Exp Pathol. 2015 Sep 1;8(9):10565-74. PubMed PMID: 26617766; PubMed Central PMCID: PMC4637581.
Zhou QH, Fan YG, Bu H, Wang Y, Wu N, Huang YC, Wang G, Wang XY, Qiao YL. China national lung cancer screening guideline with low-dose computed tomography (2015 version). Thorac Cancer. 2015 Nov;6(6):812-8. doi: 10.1111/1759-7714.12287. PubMed PMID: 26557925; PubMed Central PMCID: PMC4632939.
Bao J, Sun J, Zhou Y, Wu Q, Wang Yujia, Li L, Jiang X, Ma L, Xie Mingjun, Shi Y, Bu H. [Anticoagulant Ability and Heparinization of Decellularized Biomaterial Scaffolds]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2015 Jun;32(3):594-8. Chinese.PubMed PMID: 26485984.
Ye F, Qiu Y, Li L, Yang L, Cheng F, Zhang H, Wei B, Zhang Z, Sun L, Bu H. The Presence of EpCAM(-)/CD49f(+) Cells in Breast Cancer Is Associated with a Poor Clinical Outcome. J Breast Cancer. 2015 Sep;18(3):242-8. doi:10.4048/jbc.2015.18.3.242. PubMed PMID: 26472974; PubMed Central PMCIDMC4600688.
Lu C, Xia J, Zhou Y, Lu X, Zhang L, Gou M, Li L, Zhang X, Ji H, Zhu K, Li L, Zhang J, Yu P, Yang J, Bu H, Shi Y. Loss of Gsα impairs liver regeneration through a defect in the crosstalk between cAMP and growth factor signaling. J Hepatol. 2016 Feb;64(2):342-51. doi: 10.1016/j.jhep.2015.08.036. PubMed PMID:26386161.
Yang LB, Sun LY, Jiang Y, Tang Y, Li ZH, Zhang HY, Bu H, Ye F. The Clinicopathological Features of BRAF Mutated Papillary Thyroid Cancers in Chinese Patients. Int J Endocrinol. 2015;2015:642046. doi: 10.1155/2015/642046. PubMed PMID: 26273300; PubMed Central PMCID: PMC4530233.
Lu C, Zhang Z, Jiang Y, Yang Z, Yang Q, Liao D, Bu H. Primary pure carcinoid tumors of the testis: Clinicopathological and immunophenotypical characteristics of 11 cases. Oncol Lett. 2015 May;9(5):2017-2022. PubMed PMID: 26137005; PubMed Central PMCID: PMC4467263.
He Y, Wang W, Xu L, Li L, Liu J, Feng M, Bu H. Immunohistochemical Expression and Prognostic Significance of CD97 and its Ligand DAF in Human Cervical Squamous Cell Carcinoma. Int J Gynecol Pathol. 2015 Sep;34(5):473-9. doi:10.1097/PGP.0000000000000200. PubMed PMID: 26107567.
Zhou P, Xia J, Zhou YJ, Wan J, Li L, Bao J, Shi YJ, Bu H. Proportions of acetyl-histone-positive hepatocytes indicate the functional status and prognosis of cirrhotic patients. World J Gastroenterol. 2015 Jun 7;21(21):6665-74. doi:10.3748/wjg.v21.i21.6665. PubMed PMID: 26074705; PubMed Central PMCIDMC4458777.
Lu XF, Zhou YJ, Zhang L, Ji HJ, Li L, Shi YJ, Bu H. Loss of Dicer1 impairs hepatocyte survival and leads to chronic inflammation and progenitor cell activation. World J Gastroenterol. 2015 Jun 7;21(21):6591-603. doi:10.3748/wjg.v21.i21.6591. PubMed PMID: 26074697; PubMed Central PMCIDMC4458769.
Bao J, Wu Q, Sun J, Zhou Y, Wang Y, Jiang X, Li L, Shi Y, Bu H.Hemocompatibility improvement of perfusion-decellularized clinical-scale liver scaffold through heparin immobilization. Sci Rep. 2015 Jun 1;5:10756. doi:10.1038/srep10756. PubMed PMID: 26030843.
Guideline Recommendations for Immunohistochemistry Detection in Breast Cancer Group.. [Guideline for testing of estrogen and progesterone receptors in breast cancer]. Zhonghua Bing Li Xue Za Zhi. 2015 Apr;44(4):237-9. Chinese. PubMed PMID:25975904.
Consensus Group for Neoadjuvant Chemotherapy of Breast Carcinomas.[Pathology of breast carcinomas after neoadjuvant chemotherapy: an expert consensus]. Zhonghua Bing Li Xue Za Zhi. 2015 Apr;44(4):232-6. Chinese. PubMed PMID: 25975903.
Yang W, Bu H. [Review of Guideline for Detection of HER2 in Breast Cancer (2014) after one-year release]. Zhonghua Bing Li Xue Za Zhi. 2015 Apr;44(4):227-9. Review. Chinese. PubMed PMID: 25975901.
Du Z, Zhou Y, Lu X, Li L, Lu C, Li L, Li B, Bu H, Yang J, Shi Y. Octreotide prevents liver failure through upregulating 5'-methylthioadenosine in extended hepatectomized rats. Liver Int. 2016 Feb;36(2):212-22. doi: 10.1111/liv.12863. PubMed PMID: 25944273.
Wu Q, Bao J, Zhou YJ, Wang YJ, Du ZG, Shi YJ, Li L, Bu H. Optimizing perfusion-decellularization methods of porcine livers for clinical-scale whole-organ bioengineering. Biomed Res Int. 2015;2015:785474. doi:10.1155/2015/785474. PubMed PMID: 25918720; PubMed Central PMCID: PMC4396818.
Deng L, Chen J, Zhong XR, Luo T, Wang YP, Huang HF, Yin LJ, Qiu Y, Bu H, Lv Q, Zheng H. Correlation between activation of PI3K/AKT/mTOR pathway and prognosis of breast cancer in Chinese women. PLoS One. 2015 Mar 27;10(3):e0120511. doi:10.1371/journal.pone.0120511. PubMed PMID: 25816324; PubMed Central PMCIDMC4376391.
Yang W, Wei B, Chen M, Bu H. [Evaluation of immunohistochemistry HER2 results interpretation in invasive micropapillary carcinoma of the breast]. Zhonghua Bing Li Xue Za Zhi. 2015 Jan;44(1):48-52. Chinese. PubMed PMID: 25765031.
Li Y, Guo G, Li L, Chen F, Bao J, Shi YJ, Bu H. Three-dimensional spheroid culture of human umbilical cord mesenchymal stem cells promotes cell yield and stemness maintenance. Cell Tissue Res. 2015 May;360(2):297-307. doi: 10.1007/s00441-014-2055-x. PubMed PMID: 25749992.
Lu C, Qiu Y, Lu X, Li G, Bu H. Synchronous diffuse ganglioneuromatosis and multiple schwannomas of the colon: A case report and literature review. Exp Ther Med. 2015 Mar;9(3):733-736. PubMed PMID: 25667620; PubMed Central PMCID: PMC4316863.
Zhang Z, Bu H, Huang H, Zhang J, Lang Z, Zhao T, Wang J, Liao D, Wei B. [Matrix-producing metaplastic carcinoma: a clinicopathologic and prognostic analysis of 16 cases with review of literature]. Zhonghua Bing Li Xue Za Zhi. 2014 Aug;43(8):528-32. Chinese. PubMed PMID: 25346122.
Wang Y, Bao J, Wu Q, Zhou Y, Li Y, Wu X, Shi Y, Li L, Bu H. Method for perfusion decellularization of porcine whole liver and kidney for use as a scaffold for clinical-scale bioengineering engrafts. Xenotransplantation. 2015 Jan-Feb;22(1):48-61. doi: 10.1111/xen.12141. PubMed PMID: 25291435.
Yin C, Zhang T, Qiao L, Du J, Li S, Zhao H, Wang F, Huang Q, Meng W, Zhu H, Bu H, Li H, Xu H, Mo X. TLR7-expressing cells comprise an interfollicular epidermal stem cell population in murine epidermis. Sci Rep. 2014 Jul 25;4:5831. doi: 10.1038/srep05831. PubMed PMID: 25060222.
Wu HK, Wang W, Li H, Bu H, Zhang P. [The mechanism of ciclosporin A regulating the expression of LOX-1 on vascular endothelium of hyperlipidemic rats]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2014 May;45(3):371-5. Chinese. PubMed
PMID: 24941799.
Guideline Recommendations for HER2 Detection in Breast Cancer Group.Guidelines for HER2 detection in breast cancer, the 2014 version]. Zhonghua Bing Li Xue Za Zhi. 2014 Apr;43(4):262-7. Chinese. PubMed PMID: 24915819.
Zhong X, Luo T, Zheng H, Bu H. [New challenges of personalized therapy for breast cancer to pathologists]. Zhonghua Bing Li Xue Za Zhi. 2014 Apr;43(4):219-21. Chinese. PubMed PMID: 24915809.
Bu H, Yang W. [To improve the quality of pathologic diagnosis through standardized HER2 testing]. Zhonghua Bing Li Xue Za Zhi. 2014 Apr;43(4):217-8. Chinese. PubMed PMID: 24915808.
Qiu Y, Pu T, Li L, Cheng F, Lu C, Sun L, Teng X, Ye F, Bu H. The expression of aldehyde dehydrogenase family in breast cancer. J Breast Cancer. 2014 Mar;17(1):54-60. doi: 10.4048/jbc.2014.17.1.54. PubMed PMID: 24744798; PubMed Central PMCID: PMC3988343.
Zhang Z, Wang J, Skinner KA, Shayne M, Hajdu SI, Bu H, Hicks DG, Tang P. Pathological features and clinical outcomes of breast cancer according to levels of oestrogen receptor expression. Histopathology. 2014;65(4):508-16. doi: 10.1111/his.12412. PubMed PMID: 24620991.
Cheng L, Bu H, Portillo JA, Li Y, Subauste CS, Huang SS, Kern TS, Lin F. Modulation of retinal Müller cells by complement receptor C5aR. Invest Ophthalmol Vis Sci. 2013 Dec 17;54(13):8191-8. doi: 10.1167/iovs.13-12428. PubMed PMID: 24265019; PubMed Central PMCID: PMC3867184.
Ye F, Chen Y, He D, Jian SY, Zheng K, Li GD, Bu H. [Detection of Mycobacterium tuberculosis complex in paraffin-embedded tissues by real-time fluorescent quantitative polymerase chain reaction]. Zhonghua Bing Li Xue Za Zhi. 2013 Aug;42(8):534-7. Chinese. PubMed PMID: 24246919.
Huang D, Lu N, Fan Q, Sheng W, Bu H, Jin X, Li G, Liu Y, Li X, Sun W, Zhang H, Li X, Zhou Z, Yan M, Wang X, Sha W, Ji J, Cheng X, Zhou Z, Xu J, Du X. HER2 status in gastric and gastroesophageal junction cancer assessed by local and central laboratories: Chinese results of the HER-EAGLE study. PLoS One. 2013 Nov 14;8(11):e80290. doi: 10.1371/journal.pone.0080290. PubMed PMID: 24244671; PubMed Central PMCID: PMC3828190.
Zhang Z, Wang J, Tacha DE, Li P, Bremer RE, Chen H, Wei B, Xiao X, Da J, Skinner K, Hicks DG, Bu H, Tang P. Folate receptor α associated with triple-negative breast cancer and poor prognosis. Arch Pathol Lab Med. 2014 Jul;138(7):890-5. doi: 10.5858/arpa.2013-0309-OA. PubMed PMID: 24028341.
Zhi X, Wu Y, Ma S, Wang T, Wang C, Wang J, Shi Y, Lu Y, Liu L, Liu D, Chen D, Yang Y, Du X, Bu H, Zhou Q, Jang G, Han B, Cheng G, Cheng Y, Jiao S. [Chinese guidelines on the diagnosis and treatment of primary lung cancer (2011version)]. Zhongguo Fei Ai Za Zhi. 2012 Dec;15(12):677-88. doi:10.3779/j.issn.1009-3419.2012.12.01. Chinese. PubMed PMID: 23249713.
Ni Y, Xie X, Bu H, Zhang Z, Wei B, Yin L, Chen M, Chen H, Zhang H. Concurrent primary angiosarcoma and invasive ductal carcinoma in the same breast. J Clin Pathol. 2013 Mar;66(3):263-4. doi: 10.1136/jclinpath-2012-201233. PubMed PMID:23172554.
Yin L, Chen M, Ye F, Bu H, Bai H, Yu J, Zhang H. A poorly differentiated synovial sarcoma arising from the pulmonary valve. Cardiovasc Pathol. 2013 Nov-Dec;22(6):501-2. doi: 10.1016/j.carpath.2013.04.004. PubMed PMID: 23701986.
Xia J, Zhou Y, Ji H, Wang Y, Wu Q, Bao J, Ye F, Shi Y, Bu H. Loss of histone deacetylases 1 and 2 in hepatocytes impairs murine liver regeneration through Ki67 depletion. Hepatology. 2013 Dec;58(6):2089-98. doi: 10.1002/hep.26542. PubMed PMID: 23744762.
Cheng L, Shi Y, Ye F, Bu H. Osteoinduction of calcium phosphate biomaterials in small animals. Mater Sci Eng C Mater Biol Appl. 2013 Apr 1;33(3):1254-60. doi:10.1016/j.msec.2012.12.023. PubMed PMID: 23827569.
Ye F, Chen Y, He D, Jian SY, Zheng K, Li GD, Bu H. Detection of Mycobacterium tuberculosis complex in paraffin-embedded tissues by real-time fluorescent quantitative polymerase chain reaction . Zhonghua Bing Li Xue Za Zhi. 2013 Aug;42(8):534-7. Chinese. PubMed PMID: 24246919.
Cheng L, Shi Y, Ye F, Bu H. Osteoinduction of calcium phosphate biomaterials in small animals. Mater Sci Eng C Mater Biol Appl. 2013 Apr 1;33(3):1254-60. doi: 10.1016/j.msec.2012.12.023. Epub 2012 Dec 9. PubMed PMID: 23827569.
Ke Q, Yang RN, Ye F, Wang YJ, Wu Q, Li L, Bu H. Impairment of liver regeneration by the histone deacetylase inhibitor valproic acid in mice. J Zhejiang Univ Sci B. 2012 Sep;13(9):695-706. PubMed PMID: 22949360; PubMed Central PMCID: PMC3437367.
Guo G, Xia J, Bao J, Sun HQ, Shi YJ, Bu H. Expression of SOCS3 throughout liver regeneration is not regulated by DNA methylation. Hepatobiliary Pancreat Dis Int. 2012 Aug 15;11(4):401-6. PubMed PMID: 22893467.
Zhou P, Xia J, Guo G, Huang ZX, Lu Q, Li L, Li HX, Shi YJ, Bu H. A Macaca mulatta model of fulminant hepatic failure. World J Gastroenterol. 2012 Feb 7;18(5):435-44. doi: 10.3748/wjg.v18.i5.435. PubMed PMID: 22346249; PubMed Central PMCID: PMC3270505.
Shi Y, Sun H, Bao J, Zhou P, Zhang J, Li L, Bu H. Activation of inactive hepatocytes through histone acetylation: a mechanism for functional compensation after massive loss of hepatocytes. Am J Pathol. 2011 Sep;179(3):1138-47. doi: 10.1016/j.ajpath.2011.05.029. Epub 2011 Jul 16. PubMed PMID: 21763259; PubMed Central PMCID: PMC3157283.
Yang RN, Ye F, Cheng LJ, Wang JJ, Lu XF, Shi YJ, Fan HS, Zhang XD, Bu H. Osteoinduction by Ca-P biomaterials implanted into the muscles of mice. J Zhejiang Univ Sci B. 2011 Jul;12(7):582-90. doi: 10.1631/jzus.B1000204. PubMed PMID: 21726066; PubMed Central PMCID: PMC3134847.
Bao J, Shi Y, Sun H, Yin X, Yang R, Li L, Chen X, Bu H. Construction of a portal implantable functional tissue-engineered liver using perfusion-decellularized matrix and hepatocytes in rats. Cell Transplant. 2011;20(5):753-66. doi: 10.3727/096368910X536572. Epub 2010 Nov 5. PubMed PMID: 21054928.
Zhang R, Chen HJ, Wei B, Zhang HY, Pang ZG, Zhu H, Zhang Z, Fu J, Bu H. Reproducibility of the Nottingham modification of the Scarff-Bloom-Richardson histological grading system and the complementary value of Ki-67 to this system. Chin Med J (Engl). 2010 Aug 5;123(15):1976-82. PubMed PMID: 20819528.
Yin X, Wu T, Yan Y, Zhang H, Bu H. Treatment for leiomyosarcoma and leiomyoma in children with HIV infection. Cochrane Database Syst Rev. 2010 May 12;(5):CD007665. doi: 10.1002/14651858.CD007665.pub2. Review. PubMed PMID: 20464756.
Wang W, Tang T, Zhang P, Bu H. Postconditioning attenuates renal ischemia-reperfusion injury by preventing DAF down-regulation. J Urol. 2010 Jun;183(6):2424-31. doi: 10.1016/j.juro.2010.01.066. Epub 2010 Apr 18. PubMed PMID: 20403613.
Zhang HY, Ke Q, Zhang Z, Zhang R, Fu J, Chen HJ, Wei B, Bu H. Expression of beta-catenin and estrogen receptor in desmoid-type fibromatosis . Sichuan Da Xue Xue Bao Yi Xue Ban. 2010 Jan;41(1):101-5. Chinese. PubMed PMID: 20369480.
Tu Z, Cohen M, Bu H, Lin F. Tissue distribution and functional analysis of Sushi domain-containing protein 4. Am J Pathol. 2010 May;176(5):2378-84. doi: 10.2353/ajpath.2010.091036. Epub 2010 Mar 26. PubMed PMID: 20348246; PubMed Central PMCID: PMC2861102.
Tu Z, Li Q, Bu H, Lin F. Mesenchymal stem cells inhibit complement activation by secreting factor H. Stem Cells Dev. 2010 Nov;19(11):1803-9. doi: 10.1089/scd.2009.0418. Epub 2010 Aug 1. PubMed PMID: 20163251; PubMed Central PMCID: PMC3136717.
Zhang P, Yu P, Wang W, Zhang L, Li S, Bu H. An effective method for the quantitative detection of porcine endogenous retrovirus in pig tissues. In Vitro Cell Dev Biol Anim. 2010 May;46(5):408-10. doi: 10.1007/s11626-009-9264-8. Epub 2010 Jan 28. PubMed PMID: 20108128.
Shi Y, Tu Z, Bao J, Sun H, Wang W, Luo G, Li S, Li Y, Bu H. Urinary connective tissue growth factor increases far earlier than histopathological damage and functional deterioration in early chronic renal allograft injury. Scand J Urol Nephrol. 2009;43(5):390-9. doi: 10.3109/00365520903142244. PubMed PMID: 19921985.
Cheng L, Ye F, Yang R, Lu X, Shi Y, Fan H, Bu H. Osteoinduction of hydroxyapatite tricalcium phosphate bioceramics in mice with a fractured fibula. Acta Biomater. 2010;6(4):156974.doi: 10.1016/j.actbio.2009.10.050.
Yang Y, Wei B, Zhang Z, Tang Y, Fu J, Liao DY, Li FY, Bu H. Intralaboratory reproducibility of HER2 testing in breast cancer by immunohistochemistry and comparison of results obtained by different assays . Zhonghua Bing Li Xue Za Zhi. 2009 Jan;38(1):2934. Chinese. PubMed PMID: 19489222.
Wang JJ, Ye F, Cheng LJ, Shi YJ, Bao J, Sun HQ, Wang W, Zhang P, Bu H. Osteogenic differentiation of mesenchymal stem cells promoted by overexpression of connective tissue growth factor. J Zhejiang Univ Sci B. 2009 May;10(5):355-67. doi: 10.1631/jzus.B0820252. PubMed PMID: 19434762; PubMed Central PMCID: PMC2676415.
Meng GZ, Zhang HY, Zhang Z, Wei B, Bu H. Myofibroblastic sarcoma vs nodular fasciitis: a comparative study of chromosomal imbalances. Am J Clin Pathol. 2009 May;131(5):7019. doi: 10.1309/AJCPV6H2WSYXLKFB. PubMed PMID: 19369631.
Wang W, Zhang P, Wang J, Bu H. Cyclosporine A aggravates vascular endothelial injury in hyperlipidemic rats by down-regulating decay-accelerating factor. Biochem Biophys Res Commun. 2009 Jan 30;379(1):2731. doi: 10.1016/j.bbrc.2008.11.153. Epub 2008 Dec 12. PubMed PMID: 19070591.
Zhang P, Shi M, Wei Q, Wang K, Li X, Li H, Bu H. Increased expression of connective tissue growth factor in patients with urethral stricture. Tohoku J Exp Med. 2008 Jul;215(3):199206. PubMed PMID: 18648180.
Xu S, Wei B, Zhang H, Qing M, Bu H. Evidence of chromosomal alterations in pure usual ductal hyperplasia as a breast carcinoma precursor. Oncol Rep. 2008 Jun;19(6):1469-75. PubMed PMID: 18497952.[2]&
步宏主要著作
编辑
《分子病理学:疾病的分子基础》威廉·B.科尔曼 等 著 步宏等 译,科学出版社,2012-03-01
《分子病理学进展》,四川大学出版社,2006-11-01
《病理学》,人民卫生出版社,2002-08-01
《病理学纲要》,科学出版社,:2003-05-01
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